Portrait of Longlong Li

Longlong Li

PhD Student

Department of Mechanical Engineering, Chonnam National University

Gwangju, South Korea

I develop MEMS-enabled and bioelectronic sensing platforms for engineered cardiac tissues, with an emphasis on multimodal electromechanical recording and drug cardiotoxicity evaluation.

Research Interests

  • BioMEMS sensing platforms
  • Engineered cardiac tissue
  • Multimodal recording
  • Drug cardiotoxicity screening

Research Overview

My research addresses the need for synchronized and quantitative monitoring of engineered cardiac tissues, particularly the integration of mechanical contraction, electrical activity, and drug response analysis in three-dimensional in vitro models. By combining MEMS strain sensors, microelectrode arrays, and multimodal signal processing, my work aims to develop scalable platforms for disease modeling and drug cardiotoxicity evaluation.

01

BioMEMS Sensing Platforms

Designing flexible microsystems and MEMS-based sensor architectures for biological signal acquisition in soft tissue environments.

02

Engineered Cardiac Tissue Monitoring

Building integrated platforms to evaluate contraction, maturation, and tissue-level coupling in engineered cardiac constructs.

03

Multimodal Electromechanical Recording

Combining strain, electrical, and structural readouts to observe dynamic heart-tissue behavior in real time.

04

Drug Cardiotoxicity Evaluation

Translating cardiac microsystems into quantitative screening tools for safety assessment, long-term monitoring, and disease-model studies.

Featured Projects

Selected projects that represent my recent academic and engineering trajectory.

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Hypoxia model figure
2026.03 - Present | MNTL

Biomimetic Cardiac Hypoxia Model and Electromechanical Evaluation Platform

Building a biomimetic hypoxic cardiac model with integrated sensing workflows for electromechanical analysis under disease-relevant conditions.

High-throughput screening figure
2024.03 - 2026.03 | MNTL

High-Throughput Drug Toxicity Screening Platform Based on 3D Cardiac Tissue

Developing a 3D cardiac tissue platform for parallelized pharmacological testing with integrated electromechanical readouts.

Graphene microenvironment figure
2022.09 - 2024.03 | MNTL

Regulatory Mechanisms of Graphene Conductive Microenvironments in Cardiomyocyte Electrophysiological Communication and Maturation

Investigating how graphene-based conductive microenvironments modulate cardiomyocyte communication, maturation, and functional electrophysiology.

Selected Publications

Representative papers highlighting my recent work in bioelectronic sensing, cardiac tissue platforms, and translational biomaterials.

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  1. [1] Graphene SU-8 platform for enhanced cardiomyocyte maturation and intercellular communication in cardiac drug screening Longlong Li, Arunkumar Shanmugasundaram, Jongyun Kim, Nomin-Erdene Oyunbaatar, Pooja P. Kanade, Seong-Eung Cha, Daeyun Lim, Chil-Hyoung Lee, Young-Baek Kim, Bong-Kee Lee, Eung-Sam Kim, Dong-Weon Lee. ACS Nano, 2024, 18(49): 33293-33309. Link
  2. [2] Harnessing native blueprints for designing bioinks to bioprint functional cardiac tissue Mst Zobaida Akter, Fatima Tufail, Ashfaq Ahmad, Yoon Wha Oh, Jung Min Kim, Seoyeon Kim, Md Mehedee Hasan, Longlong Li, Dong-Weon Lee, Yong Sook Kim, Su-jin Lee, Hyung-Seok Kim, Youngkeun Ahn, Yeong-Jin Choi, Hee-Gyeong Yi. iScience, 2025, 28(3). Link
  3. [3] Development of multifunctional PAA-alginate-carboxymethyl cellulose hydrogel-loaded fiber-reinforced biomimetic scaffolds for controlled release of curcumin Kamrun Nahar Fatema, Longlong Li, Khurshid Ahmad, Jongyun Kim, Dong-Weon Lee. International Journal of Biological Macromolecules, 2025, 301: 140449. Link
  4. [4] Air-Breakdown Triboelectric Nanogenerator Inspired by Transistor Architecture for Low-Force Human-Machine Interfaces Karthikeyan Munirathinam, Longlong Li, Arunkumar Shanmugasundaram, Jongsung Park, Dong-Weon Lee. Nano-Micro Letters, 2026, 18(1): 251. Link

Academic Highlights

A quick view of the full academic record documented across the dedicated archive pages.

Contact

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Location
Gwangju, South Korea