Microfabrication
Photolithography, metal deposition, SU-8 / PI processing, MEMS sensor fabrication, device packaging, sensor characterization.
Curriculum Vitae
Longlong Li
PhD Student
BioMEMS / Biosensors / Engineered Cardiac Tissue Monitoring
Department of Mechanical Engineering, Chonnam National University
Gwangju, South Korea
This CV page is optimized for fast reading by HR reviewers, research institutes, and academic collaborators, while full records remain available through the archive pages and downloadable full CV.
Profile
PhD student specializing in BioMEMS, multimodal biosensors, engineered cardiac tissue monitoring, and drug cardiotoxicity evaluation. Experienced in MEMS device design, microfabrication, cell and tissue culture, sensing system integration, and multimodal biosignal analysis. My research focuses on integrating strain sensors, microelectrode arrays, and 3D bioelectronic platforms for synchronized and quantitative assessment of cardiac tissue function.
Education
- 2022-Present | Ph.D. in Mechanical Engineering, Chonnam National University, Gwangju, South Korea
- 2018-2022 | B.Eng. in Mechanical Engineering, Wenzhou University, Wenzhou, China
Cross-links
Research Experience
- Designed and developed BioMEMS-based multimodal sensing platforms for engineered cardiac tissues.
- Integrated strain sensors and microelectrode arrays to monitor mechanical contraction and electrical activity in cardiac tissue models.
- Established 3D engineered heart tissue culture and drug stimulation workflows for cardiotoxicity screening and disease modeling.
- Developed MATLAB / Python-based analysis workflows for extracting contraction amplitude, beating frequency, field potential features, and electromechanical coupling parameters.
- Built experimental measurement systems involving low-noise signal acquisition, microscopy, sensor calibration, and hardware integration.
Technical Skills
Biosensing
Strain sensors, microelectrode arrays, electromechanical monitoring, low-noise signal acquisition, sensor calibration.
Cell & Tissue Engineering
NRVM / hiPSC-CMs culture, engineered heart tissue construction, collagen / dECM bioinks, drug stimulation experiments, immunostaining.
Data Analysis
MATLAB, Python, cardiac signal processing, feature extraction, visualization, statistical analysis.
System Integration
DAQ systems, amplifier circuits, microscopy, automated measurement platforms, prototype development.
Selected Projects
Current PhD-stage projects are presented with role and contribution highlights.
Bioinspired Hypoxic Cardiac Model and Electromechanical Evaluation Platform
- Developed an in vitro cardiac hypoxia model combined with multimodal electromechanical readouts.
- Integrated mechanical contraction sensing and electrical activity recording for functional assessment of engineered cardiac tissues.
- Applied the platform to evaluate cardiac tissue response under disease-relevant microenvironmental conditions.
High-Throughput Drug Toxicity Screening Platform Based on 3D Cardiac Tissues
- Designed and optimized a 3D cardiac tissue-based sensing platform for drug cardiotoxicity evaluation.
- Integrated strain-based mechanical sensing and electrophysiological readouts.
- Supported long-term monitoring and multiparametric analysis of drug-induced functional responses.
Graphene-Conductive Microenvironment for Cardiomyocyte Maturation and Electrophysiological Communication
- Investigated conductive microenvironment effects on cardiomyocyte maturation and intercellular communication.
- Developed graphene/SU-8-based platforms for cardiac tissue functional enhancement.
- Contributed to journal publication and conference outputs.
Earlier engineering projects, including smart trash bin development, customized food 3D printing, and toy-storage robotics, are preserved in the full Academic CV.
Selected Publications
Representative outputs emphasizing cardiac sensing, bioelectronic integration, and translational biomaterials.
- [1] Graphene SU-8 platform for enhanced cardiomyocyte maturation and intercellular communication in cardiac drug screening ACS Nano, 2024, 18(49): 33293-33309. Link
- [2] Harnessing native blueprints for designing bioinks to bioprint functional cardiac tissue iScience, 2025, 28(3). Link
- [3] Development of multifunctional PAA-alginate-carboxymethyl cellulose hydrogel-loaded fiber-reinforced biomimetic scaffolds for controlled release of curcumin International Journal of Biological Macromolecules, 2025, 301: 140449. Link
- [4] Enhancing cardiomyocyte maturation through PEDOT:PSS-coated surfaces and mechanical stimulation with strain sensors Journal of Micromechanics and Microengineering, 2025, 35(4): 045002. Link
- [5] Air-Breakdown Triboelectric Nanogenerator Inspired by Transistor Architecture for Low-Force Human-Machine Interfaces Nano-Micro Letters, 2026, 18(1): 251. Link
Selected Conferences
Key international conference contributions relevant to BioMEMS and cardiac microsystems.
2024
Enhancing Cardiomyocyte Maturation via Mechanical Stimulation of 3D Printed Cardiac Tissue Using a Origami-based 3D Sensor and Magnetic Fields
IEEE NANOMED 2024, Hawaii, USA | Longlong Li, Haolan Sun, Jong-Yun Kim, Yun-Jin Jeong, Bong-Kee Lee, Eung-Sam Kim, Dong-Weon Lee
Oral Presentation | Link
2025
A Dual-Detection Approach for Cardiotoxicity Screening: Utilizing Nano Silicon Strain Sensor and Mea to Monitor Contractility and Field Potential in Cardiomyocytes
IEEE MEMS 2025, Kaohsiung, Taiwan | Haolan Sun, Longlong Li, Dong-Weon Lee
Oral Presentation | Link
2025
Origami-Inspired 3D Sensor Platform for Real-Time Electromechanical Coupling Analysis in Engineered Heart Tissues
IEEE SENSORS 2025, Vancouver, Canada | Longlong Li, Fatima Tufail, Haolan Sun, Jongyun Kim, Hee-Gyeong Yi, Dong-Weon Lee
Poster Presentation | Link
2025
Development of a Multi-Channel Wireless Monitoring Platform for Long-Term Cardiomyocyte Contraction Assessment Using a Polymer Cantilever with integrated Sensor
MicroTAS 2025, Adelaide, Australia | Ke Liu, Haolan Sun, Longlong Li, Dong-Weon Lee
Poster Presentation
2026
Multimodal Microelectrode-Microcantilever Array for Electromechanical Analysis of Cardiomyocyte Tissue in Drug Testing
IEEE MEMS 2026, Salzburg, Austria | Haolan Sun, Longlong Li, Eung-Sam Kim, Bong-Kee Lee, Dong-Weon Lee
Oral Presentation | Link
Patent Summary
15
Total Patents
4
Invention Patents
3
Granted Inventions
11
Utility Models
- Vertical-Folding-Based Clothes Folding Machine
Granted Invention Patent, CN113186699B, 2023-02-07. - Household Intelligent Toy Storage Robot
Granted Invention Patent, CN112407980B, 2022-01-18. - Automatic Potato Harvester
Utility Model Patent, CN216415123U, 2022-05-03. - Intelligent Launch-and-Recovery Management Device for UAV Swarms
Utility Model Patent, CN216269980U, 2022-04-12.
Awards
2025
BK21 Fellowship Scholarship
Academic Fellowship
2025
RLRC Outstanding Graduate Student
Graduate Recognition
2021
China National Scholarship
National Scholarship
2019
Zhejiang Provincial Government Scholarship
Provincial Scholarship
Academic CV Scope
- The downloadable full Academic CV preserves the complete publication, conference, patent, project, and award record.
- The downloadable 2-page Resume is optimized for industry, R&D engineer, biosensor engineer, and biomedical device-related applications.
- Full education details remain in the Academic CV and the dedicated archive pages.